Sertraline, a widely used antidepressant in humans, is also prescribed for animals like dogs and cats to treat anxiety, obsessive-compulsive disorders, and behavioral issues. But what happens if a human takes sertraline meant for animals? Is it safe? What are the risks? This article explores everything you need to know about animal sertraline, its differences from human medication, and the potential dangers of taking it.
Understanding Sertraline: What Is It?
Sertraline is a Selective Serotonin Reuptake Inhibitor (SSRI) commonly prescribed to treat depression, anxiety, OCD, PTSD, and panic disorders in humans. It works by increasing serotonin levels in the brain, which helps regulate mood and behavior.
Veterinarians also prescribe sertraline for animals, primarily dogs and cats, to treat:
- Separation anxiety
- Aggressive behavior
- Obsessive-compulsive disorders (e.g., excessive licking or tail-chasing)
- Fear-based behaviors (e.g., noise phobia)
Is Animal Sertraline Different from Human Sertraline?

The active ingredient in both human and veterinary sertraline is the same. However, there are key differences in dosage, formulation, and potential additives that make taking animal sertraline risky for humans.
1. Dosage Differences
- Veterinarians prescribe sertraline at different doses based on the animal’s weight and metabolism.
- A dose meant for a 10-pound dog could be significantly lower than a human dose, making it ineffective.
- Alternatively, a dose for a large dog (50+ pounds) might be dangerously high for a human.
2. Inactive Ingredients and Additives
- Veterinary medications often contain flavors (like beef or chicken) to make them more appealing to pets.
- They may also include preservatives, binders, or fillers that could be unsafe for human consumption.
3. Regulatory Differences
- Human sertraline is regulated by the FDA, ensuring strict quality control.
- Veterinary sertraline is regulated by the FDA’s Center for Veterinary Medicine (CVM) but may have different manufacturing standards.
- Some veterinary drugs are compounded, meaning they are specially mixed by a pharmacist for an individual pet and may not meet human pharmaceutical standards.
What Happens If a Human Takes Animal Sertraline?
Taking animal sertraline as a substitute for human sertraline can lead to serious health risks, including:
1. Incorrect Dosage Risks
- A low dose may be ineffective, leading to untreated depression or anxiety.
- A high dose could cause serotonin syndrome, a dangerous condition that includes:
- Agitation
- Confusion
- Rapid heart rate
- High blood pressure
- Seizures
2. Unknown Additives
- Some veterinary formulations contain flavors, preservatives, or other chemicals not tested for human safety.
- These ingredients might cause allergic reactions, stomach irritation, or toxicity.
3. Lack of Medical Supervision
- Taking sertraline without a prescription means missing out on medical supervision, dosage adjustments, and side effect monitoring.
- SSRIs interact with many other drugs, including blood thinners, pain relievers, and other antidepressants.
What Should You Do If You Accidentally Take Animal Sertraline?

If you accidentally take a single low dose of animal sertraline, it may not cause serious harm. However, you should watch for side effects such as nausea, dizziness, or agitation.
When to Seek Medical Help
- If you took a high dose (especially from medication meant for a large dog).
- If you experience serotonin syndrome symptoms like confusion, rapid heartbeat, or sweating.
- If you have allergic reactions (rash, swelling, difficulty breathing).
Call poison control or seek emergency medical help if symptoms become severe.
Can You Use Animal Sertraline If You Can’t Afford Human Medication?
Prescription medications can be expensive, and some people may wonder if animal sertraline is a cheaper alternative. However, using pet medication for yourself is not a safe solution.
Safer Alternatives
- Generic Sertraline: Many pharmacies offer generic sertraline at a lower cost.
- Prescription Discount Programs: Programs like GoodRx, NeedyMeds, or patient assistance programs can help reduce costs.
- Ask Your Doctor: If cost is a concern, your doctor may adjust your prescription or recommend an alternative treatment.
Is It Legal to Take Animal Sertraline?

United States
- Taking medication prescribed for animals without a veterinarian’s permission is not illegal.
- However, using animal medication for humans is strongly discouraged by the FDA due to safety risks.
- Selling or distributing veterinary medication for human use can be illegal.
Other Countries
- Laws vary, but most health organizations advise against self-medicating with animal drugs.
Conclusion: Should You Take Animal Sertraline?
No, you should not take animal sertraline. While the active ingredient is the same as human sertraline, the dosage, inactive ingredients, and regulatory differences make it unsafe. If you’re struggling with access to medication, speak with a doctor or pharmacist about affordable alternatives rather than resorting to veterinary drugs.
Frequently Asked Questions (FAQs)
1. Is animal sertraline stronger than human sertraline?
Not necessarily. The strength depends on the dosage and the animal’s weight. A small pet’s dose would be too weak, while a large pet’s dose could be dangerously high for a human.
2. What should I do if I accidentally take animal sertraline?
Monitor for side effects like nausea, dizziness, or rapid heartbeat. If you experience serotonin syndrome symptoms (confusion, high fever, rapid pulse), seek emergency medical attention.
3. Can veterinarians prescribe human sertraline for pets?
Yes, veterinarians sometimes prescribe human sertraline in pet-appropriate doses. However, the reverse—humans taking animal sertraline—is unsafe.
4. What’s the difference between veterinary and human sertraline?
While the active ingredient is the same, veterinary versions may contain flavorings, preservatives, or different dosages that make them unsuitable for humans.
5. Can I get sertraline without a prescription?
No, sertraline is a prescription-only medication due to its potential side effects and interactions. If cost is an issue, look for generic options, discount programs, or assistance programs.
6. What are the risks of taking animal medications in general?
Taking any veterinary drug can expose you to incorrect dosages, harmful additives, and lack of medical supervision. Always stick to medications approved for human use.
7. How can I get cheaper sertraline legally?
- Check for generic versions.
- Use prescription discount programs.
- Look into patient assistance programs.
- Ask your doctor about lower-cost alternatives.
Final Thoughts
While it might be tempting to use animal sertraline due to cost or availability, the risks far outweigh the benefits. Always consult a doctor before taking any medication, and never substitute a veterinary drug for a human prescription. If you need help affording medication, explore legitimate options to ensure your safety and well-being.